Callistephin (Pelargonidin 3-O-glucoside) chloride is an anthocyanin. Callistephin chloride regulates the expression of inflammatory (reducing iNOS/TNF-alpha/COX-2) and apoptosis-related proteins by inhibiting p38 phosphorylation, and enhances the protective effect of Isoflurane (HY-A0134) on microglial cell damage. Callistephin chloride significantly reduces ROS levels, eliminates DPPH free radicals, protects retinal pigment epithelial cells, and inhibits lipid peroxidation. Callistephin chloride can alleviate glutamate excitotoxicity, reduce neuronal apoptosis, and protect cerebellar granule neurons. Callistephin chloride can inhibit the proliferation and metastasis of breast cancer cells by inducing apoptosis[1][2][3][4][5][6].
Molecular Weight:
468.84
Purity:
98.02
CAS Number:
[18466-51-8]
Formula:
C21H21ClO10
Target:
Apoptosis,COX,NO Synthase,p38 MAPK,Reactive Oxygen Species (ROS),TNF Receptor
Application Notes:
MCE Product type: Natural Products
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