Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and alpha-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to alpha-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis[1][2][3].
Molecular Weight:
276.29
Purity:
99.64
CAS Number:
[997-68-2]
Formula:
C11H20N2O6
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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