3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation[1].
Molecular Weight:
112.08
Purity:
99.61
CAS Number:
[496-64-0]
Formula:
C5H4O3
Target:
Lipoxygenase,MMP,Tyrosinase
Application Notes:
MCE Product type: Reference compound
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