DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT (HY-15917). DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions[1].
Molecular Weight:
312.36
Purity:
99.03
CAS Number:
[71865-37-7]
Formula:
C12H12N2O4S2
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Reference compound
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