IN04 is a inhibitor of leucine-rich repeat kinase 1 (LRRK1). IN04 can completely block the binding of ATP to the human LRRK1 kinase domain, thereby inhibiting the kinase activity of LRRK1. IN04 can significantly impair the bone resorption ability of osteoclasts, with an IC50 value of 5.72 µM. IN04 can be used for the study of osteoporosis[1][2].
Molecular Weight:
429.45
CAS Number:
[838816-57-2]
Formula:
C20H19N3O6S
Target:
Others
Application Notes:
MCE Product type: Reference compound
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