Carboxymethyl-beta-cyclodextrin sodium salt is a negatively charged beta-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-beta-cyclodextrin sodium salt forms stable aqueous complexes with Ba2+, Ca2+, Cd2+, Ni2+, Pb2+, Sr2+, and Zn2+ ions. Carboxymethyl-beta-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-beta-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-beta-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research[1][2][3].
Molecular Weight:
1541.24 (Average)
CAS Number:
[2828447-14-7]
Formula:
C56H84O49xNa
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Biochemical Assay Reagents
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