ETN029 is a DLL3 ligand. ETN029 labeled with 225Ac has dose-dependent cytotoxicity in SCLC, NEPC and metastatic melanoma cells and increases the phosphorylation of H2AX expression. ETN029 labeled with 177Lu shows rapid uptake persistent tumor retention and favorable tumor-to-kidney ratio. ETN029 can be used for cancers like SCLC and NEPC imaging and research[1].
Molecular Weight:
2142.45
Purity:
99.91
CAS Number:
[3066864-32-9]
Formula:
C101H140N22O26S2
Target:
Notch
Application Notes:
Peptides
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