IKZF2-degrader 2, CAS [[2983841-00-3]] Preis auf Anfrage

Product Overview

• Article Name: IKZF2-degrader 2, CAS [[2983841-00-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-W1128213
• Supplier Catalog Number: HY-W1128213
• Alternative Catalog Number: MCE-HY-W1128213-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

IKZF2-degrader 2 is a selective and orally active IKZF2 molecular glue degrader with DC50 values of 0.5 nM and 1.8 nM in HiBit and FACS. The IKZF2-degrader 2 mediates the ubiquitination and degradation of target proteins by recruiting the CRL4-CRBN E3 ubiquitin ligase. IKZF2-degrader 2 displays moderate degradation against SALL4 with a DC50 of 9 nM but does not induce any significant degradation towards IKZF1, IKZF3, CK1alpha and GSPT1. IKZF2-degrader 2 can be used for the study of cancer immunology[1].

Product Properties

• Molecular Weight: 509.96
• CAS Number: [2983841-00-3]
• Formula: C26H25ClFN5O3
• Target: IKZF Family,Molecular Glues

Application Notes

• Application Notes: MCE Product type: Reference compound