Cemtirestat (CMTI) is a carboxymethylated thiatriazinoindole inhibitor of aldose reductase (ALR2). Cemtirestat potently inhibits rat ocular lens ALR2 with an IC50 of 0.116 µM, and exhibits a 302-fold selectivity for rat kidney ALR1. Cemtirestat is applicable to the research of advanced diabetic complications[1].
Molecular Weight:
260.27
Purity:
95.36
CAS Number:
[309283-89-4]
Formula:
C11H8N4O2S
Target:
Aldose Reductase
Application Notes:
MCE Product type: Reference compound
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