7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC50 of 4.66 mM[1]. DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells[2].
Molecular Weight:
192.21
Purity:
97
CAS Number:
[17771-33-4]
Formula:
C11H12O3
Target:
C-type Lectin-like Receptors (CTLRs)
Application Notes:
Reference compound
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