SL010110 is an anti-hyperglycemic agent. SL010110 potently inhibits gluconeogenesis by inhibiting SIRT2, activating p300, and subsequently promoting PEPCK1 degradation. SL010110 downregulates the protein level of PEPCK1 without affecting the gene expressions of PEPCK, glucose-6-phosphatase, and fructose-1,6-bisphosphatase. SL010110 significantly improves glucose homeostasis in type 2 diabetic (T2D) mice model. SL010110 can be used for T2D research[1].
Molecular Weight:
288.30
CAS Number:
[380173-90-0]
Formula:
C16H16O5
Target:
Histone Acetyltransferase,PEPCK,Sirtuin
Application Notes:
MCE Product type: Reference compound
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