Glutamic acid sodium salt (Monosodium glutamate) is an orally active food flavor enhancer. Glutamic acid sodium salt causes ROS generation, mitochondrial dysfunction, and Apoptosis. Glutamic acid sodium salt upregulates CHOP, Grp78, and Bcl-2. Glutamic acid sodium salt impairs cognition, induces depressive-like behavior, induces hyperalgesia, and induces obesity and insulin resistance. Glutamic acid sodium salt can be used to study neurotoxicity (e.g., brain damage, cognitive impairment), metabolic disorders (e.g., obesity, insulin resistance), hepatotoxicity, and renal toxicity, as well as pain-related disorders[1][2][3][4][5][6][7][8].
Molecular Weight:
169.11
Purity:
99.23
CAS Number:
[32221-81-1]
Formula:
C5H8NNaO4
Target:
Apoptosis,Bcl-2 Family,Biochemical Assay Reagents,HSP,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Biochemical Assay Reagents
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