Salicylate (choline), CAS [[2016-36-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W338346
Supplier Catalog Number:
HY-W338346
Alternative Catalog Number:
MCE-HY-W338346-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1beta, IL-6, TNF-alpha and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer[1][2][3][4].
Molecular Weight:
241.28
CAS Number:
[2016-36-6]
Formula:
C12H19NO4
Target:
Drug Derivative,Interleukin Related,Polo-like Kinase (PLK),TNF Receptor
Application Notes:
MCE Product type: Reference compound
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