Pyrazinoylguanidine, CAS [[60398-24-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W343043
Supplier Catalog Number:
HY-W343043
Alternative Catalog Number:
MCE-HY-W343043-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
PZG
Pyrazinoylguanidine (PZG) is an analogue of the potassium sparing diuretic, Amiloride (HY-B0285). Pyrazinoylguanidine can lower the systolic and diastolic blood pressure of patients with primary hypertension, has a certain effect on reducing heart rate, and does not affect the concentrations of electrolytes such as sodium, potassium, and chloride in the blood serum. Pyrazinoylguanidine can reduce the hyperglycemia and hyperinsulinemia in type 2 diabetes, reduce the levels of triglycerides, cholesterol, and free fatty acids, and reverse the hyperglycemia and hyperlipidemia induced by thiazide diuretics, such as Hydrochlorothiazide (HY-B0252). Pyrazinoylguanidine ican nhibit the reabsorption of urea by the renal tubules, thereby increasing the clearance rate and excretion volume of urea, reducing the serum urea concentration, and minimizing its toxic accumulation[1].
Molecular Weight:
165.15
CAS Number:
[60398-24-5]
Formula:
C6H7N5O
Target:
Drug Derivative
Application Notes:
MCE Product type: Reference compound
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