Cytarabine 5-monophosphate, CAS [[7075-11-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W344074
Supplier Catalog Number:
HY-W344074
Alternative Catalog Number:
MCE-HY-W344074-5MG,MCE-HY-W344074-10MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Cytarabine 5'-monophosphate is a metabolite of the nucleoside analog Cytarabine (HY-13605), catalyzed by deoxycytidine kinase. Cytarabine 5'-monophosphate is incorporated into DNA by DNA polymerase alpha, which reduces the rate of DNA synthesis. At a concentration of 15 mM, Cytarabine 5'-monophosphate inhibits nuclear and mitochondrial DNA replication in Saccharomyces cerevisiae (S. cerevisiae). Additionally, Cytarabine 5'-monophosphate (3.5-75.1 mg/kg) improves survival in leukemia mice (L1210 mice). Cytarabine 5'-monophosphate can be used in cancer research[1].
Molecular Weight:
323.20
Purity:
98.04
CAS Number:
[7075-11-8]
Formula:
C9H14N3O8P
Target:
DNA/RNA Synthesis,Drug Metabolite
Application Notes:
MCE Product type: Reference compound
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