TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis (Apoptosis) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC50 value ranging from 0.11 to 4.49 µM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research[1].
Molecular Weight:
337.81
CAS Number:
[1389439-77-3]
Formula:
C18H16ClN5
Target:
Aurora Kinase
Application Notes:
MCE Product type: Reference compound
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