ICR-191 enhances Cisplatin (HY-17394)- DNA binding and sensitizes cells to cisplatin. ICR-191 induces a significant increase in the expression of phosphorylated H2AX (gammaH2AX), particularly in DNA-replicating cells. ICR-191 can be used for the study of leukemia[1][2].
Molecular Weight:
451.22
Purity:
95
CAS Number:
[17070-45-0]
Formula:
C19H23Cl4N3O
Target:
DNA/RNA Synthesis,Fluorescent Dye
Application Notes:
MCE Product type: Reference compound
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