V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 µg/mL and 4 µg/mL. V-161 inhibits colonization of VRE in mouse small intestine[1].
Molecular Weight:
251.33
CAS Number:
[69570-95-2]
Formula:
C16H17N3
Target:
Bacterial,Na+/K+ ATPase
Application Notes:
Reference compound
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