Pyrraline is an Nrf2 pathway activator with antioxidant and anti-inflammatory effects. Pyrraline upregulates antioxidant enzymes such as NAD(P)H dehydrogenase (NQO1) and heme oxygenase-1 (HO-1) via antioxidant response element (ARE) activation, while inhibiting NFkappaB-mediated inflammation. Pyrraline is promising for research of metabolic disorders (such as diabetic nephropathy) and cancers[1][2].
Molecular Weight:
254.28
CAS Number:
[74509-14-1]
Formula:
C12H18N2O4
Target:
Endogenous Metabolite,Keap1-Nrf2,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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