Acesulfame is a synthetic sweetener. Long-term use of Acesulfame can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion[1][2][3][4].
Molecular Weight:
163.15
Purity:
98
CAS Number:
[33665-90-6]
Formula:
C4H5NO4S
Target:
Autophagy,ERK,mTOR,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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