STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization[1].
Molecular Weight:
319.36
CAS Number:
[935685-90-8]
Formula:
C18H10FN3S
Target:
ERK,mGluR
Application Notes:
MCE Product type: Reference compound1
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