Nepsilon-(Carboxyethyl) lysine is an advanced glycation end product (AGE). Nepsilon-(Carboxyethyl) lysine induces cross-linking between proteins, thereby affecting protein structure and function and causing protein denaturation. Nepsilon-(Carboxyethyl) lysine binds to the RAGE receptor, affects cell signal transduction, and regulates processes such as inflammatory responses, cell proliferation, and apoptosis. Nepsilon-(Carboxyethyl) lysine affects glutamate transporters, reduces glutamate uptake and S100beta protein secretion, influences neurotransmission in the nervous system, and exhibits diabetes-related neurotoxicity[1][2].
Molecular Weight:
218.25
Purity:
99.9
CAS Number:
[5746-03-2]
Formula:
C9H18N2O4
Target:
Apoptosis,EAAT
Application Notes:
MCE Product type: Reference compound1
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