Nepsilon-(Carboxyethyl)lysine is an advanced glycation end product (AGE). Nepsilon-(Carboxyethyl)lysine causes cross-linking between proteins, affects the structure and function of proteins, and leads to protein denaturation. Nepsilon-(Carboxyethyl)lysine binds to RAGE receptors, affects cell signaling, regulates processes such as inflammatory response, cell proliferation and apoptosis. Nepsilon-(Carboxyethyl)lysine affects glutamate transporter, reduces glutamate uptake and S100B protein secretion, affects neurotransmission in the nervous system, and exhibits diabetic-related neurotoxicity[1][2].
Molecular Weight:
218.25
Purity:
99.9
CAS Number:
[5746-03-2]
Formula:
C9H18N2O4
Target:
EAAT
Application Notes:
MCE Product type: Reference compound1
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