GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC50 of 0.11 µM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 (IC50 > 100 µM). GSTO1-IN-3 enhances the cytotoxicity of Cisplatin (HY-17394) against human breast cancer cells. GSTO1-IN-3 inhibits IL-1beta release in mouse bone marrow-derived macrophage (BMDM) cells. GSTO1-IN-3 attenuates inflammation in mice. GSTO1-IN-3 can be used for breast cancer and inflammation research[1].
Molecular Weight:
251.75
CAS Number:
[158890-32-5]
Formula:
C14H18ClNO
Target:
Glutathione S-transferase,Interleukin Related
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
