Nemazoline (A-57219) is selective alpha-adrenergic agent with alpha1-agonist/alpha2-antagonist activity, which is used as a nasal decongestant. Nemazoline produces decongestion by alpha1-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of alpha2-antagonism. Nemazoline also blocks endogenous noradrenaline-mediated alpha 2-constriction of the resistance vessels[1].
Molecular Weight:
244.12
CAS Number:
[130759-56-7]
Formula:
C10H11Cl2N3
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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