Nurr1 agonist 2 (Compound 7) is a Nurr1 agonist (EC50: 0.07 µM). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 µM. Nurr1 agonist 2 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].
Molecular Weight:
310.37
Purity:
98.03
CAS Number:
[742058-34-0]
Formula:
C18H14O3S
Target:
Nuclear Hormone Receptor 4A/NR4A
Application Notes:
MCE Product type: Reference compound1
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