Y-27632-d4 (hydrochloride hydrate) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W700452
Supplier Catalog Number:
HY-W700452
Alternative Catalog Number:
MCE-HY-W700452-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Y-27632-d4 hydrochloride hydrate is the deuterium labeled Y-27632 hydrochloride hydrate (HY-10071A). Y-27632 hydrochloride hydrate is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 hydrochloride hydrate attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 hydrochloride hydrate also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 hydrochloride hydrate primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4][5][6][7].
Molecular Weight:
342.30
Formula:
C14H21D4Cl2N3O2
Target:
Apoptosis,Isotope-Labeled Compounds,ROCK
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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