RepSox hydrochloride is a potent and selective inhibitor of transforming growth factor-beta receptor I/activin-like kinase 5 (TGF-beta-RI/ALK5). RepSox hydrochloride inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox hydrochloride can be used in the study of obesity and related metabolic diseases such as type 2 diabetes.
Molecular Weight:
323.78
CAS Number:
[2319939-07-4]
Formula:
C17H14ClN5
Target:
Anaplastic lymphoma kinase (ALK),TGF-beta/Smad
Application Notes:
MCE Product type: Reference compound
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