Flupirtine (hydrochloride), CAS [[33400-45-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W709349
Supplier Catalog Number:
HY-W709349
Alternative Catalog Number:
MCE-HY-W709349-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
D 9998 (hydrochloride)
Flupirtine (D 9998) hydrochloride is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. Flupirtine hydrochloride is a neuronal potassium channel opener (Kv7 activator), a NMDA receptor antagonist and a GABA receptor activator. Flupirtine hydrochloride stabilizes blood-brain-barrier integrity, reduces oxidative stress and brain leukocyte infiltration, enhances angioneurogenesis, suppresses calcium influx, stabilizes neuronal resting membrane potential, and counteracts focal cerebral ischemia. Flupirtine hydrochloride exhibits analgesic, muscle relaxant properties, protects neurons from excitotoxic, ischemic, or cytokine-mediated death. Flupirtine hydrochloride functions as a non-opioid analgesic without antipyretic or antiphlogistic properties, shows no relevant affinity to opiate receptor. Flupirtine hydrochloride can be used for the research of focal cerebral ischemia, pain, Alzheimers disease, or multiple sclerosis[1][2][3][4][5].
Molecular Weight:
340.78
CAS Number:
[33400-45-2]
Formula:
C15H18ClFN4O2
Target:
GABA Receptor,iGluR,Potassium Channel
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
