MK-8666 is a potent and selective partial GPR40 agonist (EC50 = 0.54 nM for human GPR40). MK-8666 shows selectivity over GPR119, GPR43, GPR41, GPR120, and other G-protein-coupled receptors (GPCRs). MK-8666 reduces glucose in the rodent. MK-8666 can be used for type 2 diabetes research[1][2].
Molecular Weight:
521.62
CAS Number:
[1544739-75-4]
Formula:
C29H31NO6S
Target:
Free Fatty Acid Receptor
Application Notes:
MCE Product type: Reference compound
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