Migalastat hydrochloride-15N (GR181413A-15N) is the 15N-labeled Migalastat hydrochloride (HY-14929A). Migalastat (GR181413A free base) hydrochloride is an orally active alpha-galactosidase A molecular chaperone, with an IC50 value of 0.04 µM for human alpha-Gal A. Migalastat binds to the active site of certain unstable mutant forms of alpha-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant alpha-galactosidase A to exhibit biological activity[1].
Molecular Weight:
200.63
CAS Number:
[1219134-37-8]
Formula:
C6H14Cl 15NO4
Target:
Glycosidase,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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