Cefetamet-d3 (Ro 15-8074-d3, Deacetoxycefotaxime-d3) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 µg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis[1][2][3][4][5].
Molecular Weight:
400.45
Formula:
C14H12D3N5O5S2
Target:
Antibiotic,Bacterial,Drug Metabolite,Isotope-Labeled Compounds,Penicillin-binding protein (PBP)
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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