NAPQI-d3 (N-Acetyl-4-benzoquinone Imine-d3) is the deuterium labeled NAPQI (HY-W017464). NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver[1][2].
Molecular Weight:
152.17
Formula:
C8H4D3NO2
Target:
Drug Metabolite,Endogenous Metabolite,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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