Triclosan-13C12, CAS [[1365620-36-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W747491
Supplier Catalog Number:
HY-W747491
Alternative Catalog Number:
MCE-HY-W747491-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Triclosan-13C12 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models[1][2][3][4].