Cannflavin A can be isolated from Cannabis sativa L.. Cannflavin A has anti-cancer, neuroprotective and anti-inflammatory activity. Cannflavin A inhibits Abeta1-42 aggregation. Cannflavin A also inhibits kynurenine-3-monooxygenase (KMO) (IC50 = 29.4 µM). Cannflavin A activates apoptosis via caspase-3 cleavage. Cannflavin A exerts anti-inflammatory effects by inhibiting pro-inflammatory enzymes, including prostaglandin E2 and cytochrome c oxidases I and II in PC12 cell line[1][2][3][4].
Molecular Weight:
436.50
Purity:
99.20
CAS Number:
[76735-57-4]
Formula:
C26H28O6
Target:
Amyloid-beta,Apoptosis,KMO
Application Notes:
MCE Product type: Natural Products
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