Iminostilbene-d10, CAS [[3044090-39-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W753956
Supplier Catalog Number:
HY-W753956
Alternative Catalog Number:
MCE-HY-W753956-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Iminostilbene-d10 is the deuterium labeled Iminostilbene (HY-N7064). Iminostilbene is a chemical precursor of carbamazepine. Additionally, Iminostilbene is an orally active inhibitor of PKM2 (Pyruvate Kinase M2) and COX2 (Cyclooxygenase-2). Iminostilbene exerts its effects by inhibiting PKM2 and its interaction with HIF-1alpha and STAT3, reducing COX2 and iNOS expression, and decreasing LPS-induced release of IL-1beta, IL-6, TNF-alpha, and MCP-1, thereby suppressing macrophage-mediated inflammatory responses and improving myocardial ischemia/reperfusion (MI/R) injury. Iminostilbene holds promise for research in inflammation regulation, cardiovascular diseases (such as MI/R injury), and macrophage-mediated immune-related diseases[1][2].
