Avapritinib-d3, CAS [[2408934-57-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W754911
Supplier Catalog Number:
HY-W754911
Alternative Catalog Number:
MCE-HY-W754911-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
BLU-285-d3
Avapritinib-d3 (BLU-285-d3) is deuterium labeled Avapritinib. Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC50s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2[1][2].
Molecular Weight:
501.58
CAS Number:
[2408934-57-4]
Formula:
C26H24D3FN10
Target:
c-Kit,Isotope-Labeled Compounds,PDGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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