ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects[1].
Molecular Weight:
228.29
CAS Number:
[794510-70-6]
Formula:
C13H16N4
Target:
MNK
Application Notes:
MCE Product type: Reference compound
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