JP-2-196 hydrochloride is a covalent molecular glue degrader targeting RNF126. JP-2-196 hydrochloride induces the formation of a ternary complex between RNF126 and target proteins (e.g., BRD4, AR-V7), promoting their ubiquitination and proteasomal degradation. JP-2-196 hydrochloride is promising for research of cancers (e.g., prostate cancer, leukemia)[1].
Molecular Weight:
310.78
Formula:
C15H19ClN2O3
Target:
E1/E2/E3 Enzyme,Molecular Glues
Application Notes:
MCE Product type: Reference compound1
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