BPD is a COX-2 and TAK1-NF-kappaB inhibitor, with an IC50 of 18.5 µM for COX-2. BPD inhibits the expression of iNOS, TNF-alpha, IL-6 and IL-1beta at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death[1].
Molecular Weight:
294.26
CAS Number:
[213481-12-0]
Formula:
C17H10O5
Target:
COX,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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