HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer[1].
Molecular Weight:
163.14
Purity:
99.97
CAS Number:
[28230-32-2]
Formula:
C7H5N3O2
Target:
HIV,STAT
Application Notes:
Reference compound
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