AAPH (2,2-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis[1]. AAPH decomposes at 37C to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis[1][2][3][4].
Molecular Weight:
271.19
Purity:
98
CAS Number:
[2997-92-4]
Formula:
C8H20Cl2N6
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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