Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings[1][2].
Molecular Weight:
174.19
Purity:
99.99
CAS Number:
[123-25-1]
Formula:
C8H14O4
Target:
Biochemical Assay Reagents,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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