DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent, although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate[1][2].
Molecular Weight:
119.16
Purity:
99.63
CAS Number:
[4637-24-5]
Formula:
C5H13NO2
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Reference compound1
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