Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
Molecular Weight:
121.14
Purity:
99.82
CAS Number:
[55-21-0]
Formula:
C7H7NO
Target:
Endogenous Metabolite,PARP
Application Notes:
MCE Product type: Reference compound
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