CASQ2 Calsequestrin-2 Dog protein

Catalog Number: NBS-RBB-LTK5CB-10
Article Name: CASQ2 Calsequestrin-2 Dog protein
Biozol Catalog Number: NBS-RBB-LTK5CB-10
Supplier Catalog Number: RBB-LTK5CB-10
Alternative Catalog Number: NBS-RBB-LTK5CB-10
Manufacturer: Nordic BioSite
Category: Proteine/Peptide
Species Reactivity: Rat
Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40--50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
NCBI: 483134
UniProt: P12637
Target: CASQ2