P-Cadherin (CDH3) Antibody, IgG1, Clone: [12H6], Mouse, Monoclonal

Catalog Number: NBT-1001-MSM1-P1ABX
Article Name: P-Cadherin (CDH3) Antibody, IgG1, Clone: [12H6], Mouse, Monoclonal
Biozol Catalog Number: NBT-1001-MSM1-P1ABX
Supplier Catalog Number: 1001-MSM1-P1ABX
Alternative Catalog Number: NBT-1001-MSM1-P1ABX-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: FC, IF, WB
Species Reactivity: Human
Immunogen: Recombinant human P-cadherin fusion protein
Alternative Names: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin
Recognizes a protein of 116kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.
Clonality: Monoclonal
Clone Designation: [12H6]
Molecular Weight: 116kDa
Isotype: IgG1
NCBI: 1001
UniProt: P22223
Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml) Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified P-Cadherin Mouse Monoclonal Antibody (12H6). Confirmation of Integrity and Purity of Antibody.