CD100 (Semaphorin-4D) Antibody, IgG1, Clone: [SEMA4D/933], Mouse, Monoclonal

Catalog Number: NBT-10507-MSM3-P1ABX
Article Name: CD100 (Semaphorin-4D) Antibody, IgG1, Clone: [SEMA4D/933], Mouse, Monoclonal
Biozol Catalog Number: NBT-10507-MSM3-P1ABX
Supplier Catalog Number: 10507-MSM3-P1ABX
Alternative Catalog Number: NBT-10507-MSM3-P1ABX-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: FC, IF
Species Reactivity: Human, Primate
Immunogen: Human recombinant SEMA4D protein
Alternative Names: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Clonality: Monoclonal
Clone Designation: [SEMA4D/933]
Molecular Weight: 50kDa (Monomer)
Isotype: IgG1
NCBI: 10507
UniProt: Q92854
Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Optimal dilution for a specific application should be determined.