Recombinant fragment (around aa100-276) of human SCGN protein (exact sequence is proprietary)
Alternative Names:
Calbindin like, CALBL, DJ501N12.8, SECRET, Secretagogin EF hand calcium binding protein, SEGN, Setagin
SCGN, also known as Secretagogin, CALBL, setagin or SECRET, is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Secretagogin (SCGN) Mouse Monoclonal Antibody (SCGN/7321). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human pancreas stained with Secretagogin (SCGN) Mouse Monoclonal Antibody (SCGN/7321). Inset: PBS instead of primary antibody, secondary only negative control.
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