FTCD / 58K Golgi Protein Antibody, IgG1, Clone: [FTCD/357], Mouse, Monoclonal

Catalog Number: NBT-10841-MSM1-P0
Article Name: FTCD / 58K Golgi Protein Antibody, IgG1, Clone: [FTCD/357], Mouse, Monoclonal
Biozol Catalog Number: NBT-10841-MSM1-P0
Supplier Catalog Number: 10841-MSM1-P0
Alternative Catalog Number: NBT-10841-MSM1-P0-20,NBT-10841-MSM1-P0-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: FC, IF, WB
Species Reactivity: Human
Immunogen: 58K Golgi Protein purified from rat liver.
Alternative Names: Formimidoyltetrahydrofolate cyclodeaminase, Formiminotetrahydrofolate cyclodeaminase, Formiminotransferase cyclodeaminase, Glutamate formiminotransferase, Glutamate formyltransferase, LCHC1
The antibody recognizes an epitope located on the microtubule-binding peripheral Golgi membrane 58 kDa protein. It is also useful for studies on the effect of microtubule-perturbing agents on the Golgi apparatus.The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively-spliced transcript variants have been found for this gene. Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi.
Clonality: Monoclonal
Clone Designation: [FTCD/357]
Molecular Weight: 59kDa
Isotype: IgG1
NCBI: 10841
UniProt: O95954
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Application Notes: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), ,Optimal dilution for a specific application should be determined.