Recombinant Chromogranin A / CHGA (Neuroendocrine Marker) Antibody, IgG2b, Clone: [rCHGA/9612], Mouse, Monoclonal

Catalog Number: NBT-1113-MSM31-P1ABX
Article Name: Recombinant Chromogranin A / CHGA (Neuroendocrine Marker) Antibody, IgG2b, Clone: [rCHGA/9612], Mouse, Monoclonal
Biozol Catalog Number: NBT-1113-MSM31-P1ABX
Supplier Catalog Number: 1113-MSM31-P1ABX
Alternative Catalog Number: NBT-1113-MSM31-P1ABX-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant full-length human CHGA protein.
Alternative Names: Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Clonality: Monoclonal
Clone Designation: [rCHGA/9612]
Molecular Weight: 68-75kDa
Isotype: IgG2b
NCBI: 1113
UniProt: P10645
Form: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.